Warsaw Medical Physics Meeting 2015

14-05-2015 09:00 to 16-05-2015 16:00

Center of New Technologies
Warsaw, Poland

Spatiotemporal dynamics of DNA damage in cells exposed to mixed beams of ionising radiations

  • 14-05-2015 12:40

The goal of this study is to analyse the kinetics of formation and repair of ionising radiation-induced foci (IRIF) in cells exposed to alpha particles, X rays and a mixed beam of both radiations. The hypothesis is that exposure to a mixed beam induces complex DNA damage above the level expected from the additive action of both radiations and the results of this analysis will be presented. The measurements are performed with human cells transfected with a plasmid coding for the DNA repair protei...

Protective effect of melatonin on γ radiation-induced sperm malformations in C57BL/6 male mice

  • 14-05-2015 13:05

Ritu Kushwaha, Dhruv K Nishad, Aseem BhatnagarBackground: Melatonin, a compound known for its antioxidant properties, scavenges free radicals and counteracts the generation of free radicals by inhibiting activity of the nitric oxide synthase.Objective: This study is intended to assess the protective efficacy of melatonin against the γ radiation induced alterations in the morphological characteristics of sperm in the cauda epididymis of C57Bl/6 mice.Materials and Methods: C57BL/6 male mice (n=12)...