Warsaw Medical Physics Meeting 2015

14-05-2015 09:00 to 16-05-2015 16:00

Center of New Technologies
Warsaw, Poland

Automated environment control using a multi-agent system for radiopharmaceuticals production

  • 14-05-2015 10:25

This paper discusses the development of an automated monitoring system in order to ensure a cGMP compliant environment inside a radiopharmaceuticals production facility. One promising technique for controlling the environment key parameters is through the use of autonomous, intelligent software agents together with an environment model. When disturbances occurs agents will react to the environment changes and automatically take action for restoring the normal values for the pressure cascades, a...

Targeting αvβ3 integrin receptors using Ga-68 labelled RGD peptides

  • 14-05-2015 10:50

The aim of this study was to target the αvβ3 integrin on tumor cells in the frame of diagnostic imaging. Due to its overexpression at the surface of cancer cells and osteoclasts, integrin αvβ3 is a bio-active receptor in several pathologic processes related to tumor growth and methastasis. As a specific transporter c(RGD)2 coupled with DOTA was used and radiolabelled with Ga-68, through automated synthesis, obtaining a PET radiotracer. During this study the eluate from an anorganic column based...